Startups Funded in 2010
18 major Ortho fundings = $240M
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Dec 2010
Bonovo (China) Hip, knee and instrument maker raises $16.5M in Series C round
Sep 2010
Ranier Technology (UK) secures $8M to commercialise its Cadisc-L spinal disc in Europe
Aug 2010
Bacterin Medical (Belgrade, MT) closes $9.2M in Private Placement. Bacterin is a developer of anti-infective coatings for medical applications and revolutionary bone graft material.
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July 2010
BioMimetic Theraeutics (Nashville, TN) raised $45M with a public offering of 5,000,000 shares of stock
DFine (San Jose, CA) VC round of $36.2M led by new investor Split Rock Partners. Funding was also contributed by new investor OrbiMed, and inside investors Prospect Venture Partners, Vanguard Ventures, BBT Fund/Apothecary Capital, Highland Capital Management and several private investors. DFine is a developer of minimally invasive solutions for treating vertebral pathologies.
Del Palma Orthopedics (Comlumbia City, IN) raised $1.4M for it’s trigger finger procedure kit. Del Palma is housed in the OrthoVation Center incubator.
Bio2Tech (Boston) $1.1M in Angel funding to develop new biomaterials, spinoff of Geo2 Technologies
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June 2010
Baxano Inc (Moutain View, CA) $30M in Series C ed by new investor CMEA Capital, founded 2005, instrumentation to restore spine function and preserve healthy tissue
Anulex Technologies (Minnetonka, MN) completes $20M in Series E financing to expand commercialization and complete the follow-up phases for Xclose
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Apr 2010
Articulinx (Cupertino, CA) raises $10M in Series B financing to further develop interpositional spacers for hand osteoarthritis. http://www.articulinx.com
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Mar 2010
Anulex Technologies (Minnetonka, MN) raises $3.8M with 11 investors. The most recent cash infusion brings Anulex’s total funding to around $52 million since 2003. The company closed its fourthround of funding in June, pulling in $10.2 million from a number of investors.Affinity Capital, Delphi Ventures, MB Venture Partners, New Enterprise Associates, SightLine Partners and Split Rock Partners
Carticept Medical, Inc., (Alpharetta, GA) a developer of innovative products for the treatment of cartilage injuries and osteoarthritis. New investor SonoSite, Inc. joined existing investors Domain Associates and New Enterprise Associates. The financing will provide funding for the expected commercial launch of the Company’s NavigatorTM Delivery System, an integrated, computer-controlled, fluid delivery system designed to automate the delivery of medication for the benefit of both the patient and physician, as well to complete patient enrollment in the clinical study of the Company’s CartivaTM Synthetic Cartilage Implant.
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Feb 2010
Intrinsic Therapeutics Inc (Woburn, MA) raised $18M out of a $20M offering, according to a regulatory filing with the federal SEC. No new investors were listed on the filing. However, previous investors New Enterprise Associates and Spray Ventures were listed as board members, both firms have been with Intrinsic since their initial investment of $7.2M in 2001. Another VC firm, New Leaf Venture Partners (formerly Sprout Group), which invested in the company’s $25M round back in 2003 was also listed on the SEC form D. The company has a total of 11 investors overall. Intrinic won the CE mark of approval for its Barricaid annular prosthesis in April, 2009. The device is a partial-disc prosthesis that enables surgeons to reconstruct the annulus (a fibrous ring around the edge of the intervertebral disc) during standard discectomies in patients with lumbar disc herniations and sciatica.
Intralink-Spine (ILS) awarded a $750,000 Small Business Innovation Research (SBIR) Grant from the National Institutes of Health (NIH) for pre-clinical studies of its NEXT technology, develoing a tissue modifying reagent that can be injected into the intervertebral disc of the human spine to increase crosslinking in the native collagen matrix
http://www.intralink-spine.com
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Jan 2010
OrthoAlign (Irving, CA) concluded its Series A financing round with a $5.2 million Series A2 tranche led by California Technology Ventures. Additional participants included Research Corporation Technologies and Okapi Venture Capital. ”This round of financing provides us with the capital to launch our first product, the KneeAlign system, in 2010, and to continue developing other products in our pipeline,” said CEO Pieter Wolters
BioCeramic Therapeutics (UK) a development-stage provider of bioactive materials for orthopaedic and dental applications, closed a $1.9M Series B financing. Participants include Imperial Innovations, Longbow Capital Partners, Comvest and Esmee Fairbairn Foundation.
http://www.bioceramictherapeutics.com/
BioPoly LLC (Fort Wayne, IN) a Schwartz Biomedical subsidiary, has raised more than $2M in its first round of equity financing. This capital will be used to complete product development and initiate launch of its first orthopaedic products into the market. http://ow.ly/WDbN
Salient Surgical Technologies (Portsmouth, NH) has raised $15 million in equity-based financing from a group of 10 unnamed investors. Founded in 1999, it was formerly known as Tissuelink Medical, Salient makes devices that stop bleeding and seal wounds by allowing surgeons to apply focused radio-frequency energy and saline solution to collagen fibers in the body. Salient raised $17.9 million in Series F in Oct 2008 shortly after withdrawing plans for an $86 million initial public offering.
MiMedx Group (Atlanta) raised $5M in Private Placement. MiMedx Group, Inc. is an integrated developer, manufacturer and marketer of patent protected biomaterial-based products and is in the process of transitioning from a development-focused concern to an operating company focused on sales growth and profitability. The proceeds of the offering will be used to support the Company’s launch of its first product, the Paradis Vaso Shield.

