List of Joint Replacement Startups

ArthroSurface (Franklin, MA) localized metal cartilage replacements for hip, knee, shoulder, and great toe, founded in 2002 when spun out of STD Med, Inc., four rounds of funding by Boston Milenia Partners http://www.arthrosurface.com
Articulinx (Cupertino, CA) polymer disc-shaped polymer inter-positional implant for finger joints to relieve OA pain, CE marked
http://www.articulinx.com/
Ascension Orthopedics, Inc. (Austin, TX) small joint replacement implants made from proprietary Pyrocarbon, four rounds of funding since its founding in 1996
http://www.ascensionortho.com
Cardo Medical, Inc. (Beverly Hills, CA) Cardo Medical was formed in February 2007 when it acquired the assets and operations of Accin Corporation, a product development company founded in 2005, products include reconstructive joint devices and spinal surgical devices, Align 360 Unicompartmental Knee System, Align 360 Patellofemoral System, Accin Total Hip System, Accin Bipolar Hip System, Accin Monopolar Hip System
http://www.cardomedical.com
ConforMIS (Burlington, MA) raised $50M in a Series D funding from a consortium of private equity firms and sovereign wealth funds. ConforMIS makes custom knee replacements based on the patient’s CT scans that only resurface the damaged cartilage area
http://www.conformis.com/
Consensus Orthopedics (Sacramento) fka Hayes Medical, full line of hip and knee products, modular hip product is UniSyn, CEO is Colleen Gray
http://www.hayesmed.com
Corentec Co., Ltd. (Seoul, Korea) founded in 2000, hips, knees, spine, biologics
http://www.corentec.com/
Flex Biomedical (Madison, WI) Angel funding – raised $150K from Wisconsin’s Technology Venture Fund and $835K from Wisconsin Investment Partners, the NEW Capital Fund and Marquette Golden Angels. Flex is developing a polymer-based joint lubricant, called Flex Polymer, to reduce pain and increase mobility in osteoarthritis patients. It’s meant to replace hyaluronic acid injection treatments that in many cases keep pain away for six months to a year, but in some cases don’t work at all. Flex Polymer is based on intellectual property licensed from Boston University. Plans to start clinicals in 2011.
OrthAlign (Irvine, CA) founded in 2008, raised $7.2M in Series A from Research Corporation Technologies and Okapi Venture Capital, LLC. OrthoAlign is developing a smaller and portable navigation system for Total Knee Arthroplasty (TKA) where spatial guidance can be attached to existing instrumentation, awaiting FDA clearance for its palm-size disposable device that attaches to instruments used in knee replacements to help surgeons do more precise cutting of the bone to improve the fit with the joint replacement
http://orth-align.com
Knee Creations, LLC. (New York) a provider of an innovative minimally invasive surgical solution to mid-to-late stage knee osteoarthritis pain; Michael J. Simpson is CEO; David Nichols is Sr VP of Product Development & Operations; founded in 2007 by Viscogliosi Brothers, $6M in Series A in 2009
Total Joint Orthopedics (Salt Lake City) stealth mode, R&D group in Austin, founder is Dr. Aaron Hofmann
http://tjoinc.com
VOT Solutions (Warsaw, IN) founded in 2005 by Dr. Ron Clark, an orthopedic surgeon in Indiana, focus is development of an arthroscopically placed partial knee implant, launched the first arthroscopically assisted uni-knee in December of 2008, called the VOT Solo Partial Knee
(http://www.votechnology.com/Index.cfm) in Warsaw IN.

