List of 27 Biologics Startups |

List of 27 Biologics Startups

 

Other Orthopedic Startups here

Advanced Biologics (Ladera Ranch, CA) biologics products designed for spinal applications, OsteoAMP, OsteoGEN, OsteoMEM.
http://advancedbiologicscorp.com

Amniox (Atltanta, GA) startup founded in 2006, focused on human amniotic membrane procured through elective Cesarean donation; preserved using the patented CRYOTEK™ Process. This unique process conserves the healing strategies innate to Amniotic Membrane
http://www.amnioxmedical.com 

Apatech (UK)  Acquired by Baxter 2010, synthetic bone repair materials, operations in London, England, Foxborough, Massachusetts, USA and Berlin, Germany, and is a world leader in bone graft technologies, selling its products in over 20 countries around the world
http://www.apatech.com/

Asperion Biologics (San Antonio) Founded by Dr Kevin Stone in 1996 under a different name.  In 2014, CE marked the Z-Lig ACL, an engineered tendon device made from a pig. 2015 plans to raise public money and to start a US clinical study. http://www.aperionbiologics.com/

Avitus Orthopaedics  Therapies (Farmington, CT) founded in 2011 by biomedical engineers in the Johns Hopkins University Center for Bioengineering Innovation and Design, raised $1M in capital in 2014, first product is a autologous bone graft harvester – Avitus Harvester  http://avitusortho.com/

Biocomposites Ltd (UK) geneX® putty pre-loaded in a syringe

Biologic Therapies (Ocala, FL) joint venture between Scorpion Medical, Inc. and Monet Medical, Inc., a medical device development company owned and operated by Dr. R. Wade McKenna, an orthopedic surgeon, and Charles Bolles, a medical device distribution expert; the Company is planning to launch an ‘Autologous Orthobiologic Therapy’
http://www.biologictherapies.com/

BioDlogics (Memphis, TN) startup founded in 2005, novel wound covering products derived from amniotic tissue
http://www.biodlogics.com/ 

BioMimetic Therapeutics (Nashville, TN) [ACQUIRED] specializes in the development and commercialization of clinically proven products to promote the healing of musculoskeletal injuries and diseases, including therapies for orthopedic and sports medicine applications.  All Augment branded products are based upon recombinant human platelet-derived growth factor (rhPDGF-BB), which is an engineered form of PDGF
http://biomimetics.com/ 

BioStructures (Newport Beach, CA)[ACQUIRED] founded in 2009, acquired by Bioventus in 2016, focused on developing innovative proprietary platforms in bioresorbable and bioactive bone graft products for a broad range of spinal surgical applications.  www.biostructures.net

BoneSupport (Lünd, Sweden) Launched a 5mL version of CERAMENT™|G antibiotic-eluting bone substitute in the EU. Starting a pivotal U.S. clinical trial for the product in 2Q16. IPO in 2017.  https://www.bonesupport.com

Bone Solutions Inc  (Dallas, TX) Funded in 2016 to launch its new magnesium-based bone void filler product, called OsteoCrete.    http://bonesolutions.net/

Cartiva (Alpharetta, GA) Cartiva® SCI is a permanent (PVA) hydrogel device that is placed in the joint to provide pain relief and mimic natural cartilage. Cartiva SCI has been used outside the United States primarily to treat patients with osteoarthritis of the first metatarsophalangeal (MTP) joint, knee and the talus. Cartiva SCI is currently available in Canada, Europe and South America. Cartiva SCI is not available for sale or use in the United States.  https://www.cartiva.net/

CollPlant (Israel) regenerative medicine company focused on intraoperative procedures to repair ACL, rotator cuff, meniscus and cartilage repair. Also developing a BioInk for 3D bio printing of tissues and organs which is based on the rhCollagen platform. Another activity is development of hard tissue repair product which enables sustained release of growth factor for spinal fusion and trauma indications.” http://www.collplant.com/

CG Bio (Korea) portfolio of allograft and synthetic bone grafts, spinal implants, growth factors http://www.cgbio.co.kr/

Nuo Therapeutics fka Cytomedix, Inc. (Rockville, MD) public NYSE Amex:GTF, AutoloGel(tm) Platelet Separation System for use in orthopedics. The application includes the option of mixing of platelet-rich plasma (“PRP”) derived by the AutoloGel(tm) System with autograft and/or allograft bone, intra-operatively, prior to application to an orthopedic site as deemed necessary by clinical use requirements.
http://www.nuot.com/

Lattice Biologics Ltd. (Toronto) an emerging personalized/precision medicine leader in the field of cellular therapies and tissue engineering, with a focus on bone, skin, and cartilage regeneration.  Targeted applications:

  • Enhancing fusion in spine surgery
  • Enhancing breast reconstruction post mastectomy for breast cancer patients
  • Sports medicine indications, including ACL repair
  • Promotion of bone regeneration in foot and ankle surgery
  • Promotion of skull healing following neurosurgery
  • Enhancing wound repair in burn victims
  • Subchondral bone defect repair in knee and other joint surgeries

http://www.latticebiologics.com/

MiMedx Group, Inc. (Atlanta)  integrated developer, manufacturer and marketer of patent protected biomaterial-based products
http://www.mimedx.com/

MX Orthopedics (Boston) bone-implant interface coatings that are dynamic, three dimensional, porous orthopedic coatings are made of biocompatible, superelastic, spacer fabric.    http://www.mxortho.com/

Orteq (London, UK) Focused on regeneration and repair products for damaged menisci and knee cartilage. Corporate headquarters and R&D in London, UK and manufacturing (by DSM) in Exton, Pennsylvania. Products: Actifit synthetic implantable scaffold with a highly-interconnected pore structure made of proprietary biocompatible and biodegradable polymer http://orteq.com/

ORTHOReBIRTH (Japan)  Cottony type, synthetic bone-void-filling material. Its main ingredients include β-TCP (β-Tricalcium Phosphate that is excellent in bioabsorbable property), PLLa (Poly Lactic Acid), and SiV (Silicone-containing Calcium Carbonate that promotes the bone formation)  http://orthorebirth.com/

OssiFi (Kansas City) Spun off from OsteoGeneX, very early stage; developing novel therapeutics to modulate the growth of bone; establishes itself as the premier company in the field of therapeutics based on the Sclerostin family  http://www.ossifi.com/

Osteonovus (Toledo, OH) spinout from the University of Toledo, synthetic bone grafting material NovoGro that can grow robust bone in just six weeks and has excellent handling properties (feels like Play-doh, resistant to lavage, sticks to wet bone, zero exotherm and is pH neutral)  http://www.osteonovus.com/

OrthoSera GmbH (Austria) regenerative medicine company harnessing the power of blood serum for Osteoarthritic bone  http://www.orthosera.com/

Rotation Medical (Plymouth, MN) bioinductive implant for rotator cuff repair is made from bovine Achilles tendon http://rotationmedical.com/

ThermoGenesis Corp (Rancho Cordova, CA) Nasdaq: KOOL, a leading supplier of innovative products for processing and storing adult stem cells

Woven Orthopedic Technologies LLC (Hartford, CT) Woven’s technology leverages a unique biotextile to enhance screw engagement by increasing surface area contact between the bone and screw, and by distributing load transfer to help bone healing and remodeling. Our technology is simple to use and will provide a cost effective solution for procedures in which screw engagement risk exists.  http://www.wovenorthopedics.com/

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