MOTH CREATES NOVEL PEPTIDE FOR SPINE FUSION (Orthopedics This Week)
Cerapedics, Inc., a privately-held orthobiologics company located in Westminster, Colorado, has received CE Mark rating in Europe and Therapeutic Goods Administration listing in Australia for the firm’s new i-FACTOR Flex FR biologic bone graft. The new biologic bone graft, designed primarily for spinal fusion surgery, features the company’s proprietary synthetic small peptide bone graft technology with the addition of purified silk fibers. The silk is claimed to provide enhanced cohesion, improved mechanical properties, and handling characteristics.
Jeff Marx, president and chief operating officer of Cerapedics, told OTW that, to the best of his knowledge, though silk has historically been used in medicine, his company is the first to use silk in allografts. The product contains silk from larva of the bombyx mori moth. The silk is purified to remove the protein sericin, which results in biocompatible fibroin fibers that enhance cohesion and mechanical properties.
As Marx explained, while the original product worked well in confined spaces, such as cages, “the addition of silk improved interoperative handling charac...
