What are the remaining “Unmet Clinical Needs” in Orthopedics?
I am publicly compiling a list of “Unmet Clinical Needs” in Orthopedics. No agenda. Just trying to help move orthopedics forward. This list is open source and for everyone. Here is the permalink – https://orthostreams.com/2021/03/unmet/
The list, in no particular order…
#1 – Non-permanent implants for trauma and extremities. (Ossio is working on this).
#2 – Joint replacements that never need revisions. Bearing that never wear out. Bio-integrates forever with bone. (there are ~300,000 joint revisions performed in the US each year).
#3 – An ankle replacement that actually works.
#4 – The 4-part proximal humeral fracture in fragility patients. (toughest trauma problem. Patients are never happy. Surgeons are never happy with results.)
#5 – Meniscus repair that lasts. (Active Implants is working on a total meniscus replacement).
#6 – Cartilage repair that lasts forever.
#7 – Extend the life of a growth plate (physis) in a child.
#8 – Early detection and reversal of osteoporosis. (OsteoApp is doing the first part of this).
#9 – Closing large annular defects following lumbar discectomy to prevent re-herniation while enabling surgeons to preserve the disc (Intrinsic Therapeutics has brought a solution).
#10 – Modularity in ALIF cage design to allow for uncoupled height and lordosis as well as coronal correction. (Axis Spine is bringing this solution to the US market).
#11 – Slowing OA disease progression
#12 – Rotator cuff tears, especially full repair of massive tears
#13 – Lower the 25% death rate within one year of elderly hip fractures
#14 – Prediction of infection following a TJR
#15 – Osteonecrosis/AVN, both etiology and a biologic treatment
#16 – Interpositional implants to buy decades of time for early OA. (Notes: Unispacer was a good start, but pulled in 2011. NuSurface not approved in the US)
#17 – Natural repair for tendon and ligaments. (Biorez is working on this)
#18 – Nucleus replacement. (Orthoson is working on this)