Tiger Buford – retained recruiter dissecting orthopedics 
The LSI conference has emerged as a premier platform fostering collaboration between orthopedic startups and investors. Its success, in my view, stems from a “for-profit” model that prioritizes delivering the ultimate networking experience in the medtech space. While it comes with a premium price tag, it’s widely regarded as the top event of its kind.
Below are the 24 Ortho companies presenting at LSI this week (alphabetical) – https://www.lsiusasummit.com/
[ read also – A front row seat into 1,000 ortho startups. ]
https://additiveimplants.com/Additive Implants is focused on addressing unmet needs in spine surgery. The company designs and manufactures 3D printed cervical implants for fusion procedures.
https://www.agada-medical.com/Agada Medical is innovating in the field of spine surgery through their development of an Enterprise AI system named THE SPINE ORACLE™. This system aims to revolutionize spine surgery planning by using anthropometric, demographic, diagnostic data, and biomechanical models to predict surgical outcomes and costs. It leverages AI to analyze spine motion, surgical simulations and force distributions, offering prescriptive and predictive analytics to reduce unnecessary surgeries by comparing various surgical options.
https://altach.health/ Altach is developing a portfolio of biomimetic cartilage scaffolds to address the increasing global burden of cartilage defects. Utilizing Type II collagen, the company is creating biocompatible scaffolds that can be used alone or in conjunction with cell-based therapies to create an environment that is conducive to cell migration and regeneration of cartilage, as well as osteochondral defects.
https://osteoboost.com/. Bone Health Technologies is developing OsteoBoost, a wearable belt that applies mechanical stimulation to the user in order to reduce bone loss and encourage bone growth in the hips and spine.
https://www.cairasurgical.com/. CAIRA is developing software for advanced joint replacement. The software utilizes radar technology to improve navigation during manual and robotic surgery. The company’s first product is a navigation system for use during knee replacement surgery
https://www.endeavorortho.com/. Endeavor Orthopaedics is an IP-protected platform technology company focused on the integration of fracture repair with soft tissue management of deforming forces. The combination of plate/screw and suture construct in one implant allows surgeons to address not only the osseous fracture repair but also the soft-tissue deforming forces, creating a bio-mechanical advantage during patient recovery.
https://fieldorthopaedics.com/. Field Orthopaedics is dedicated to developing innovative products to meet the needs of complex fracture management, arthritis and microsurgery. The company’s portfolio of cannulated screws and intramedullary nailing system address the challenges critical to advancing hand surgery.
https://hyalex.com/Hyalex Orthopaedics is a clinical-stage medtech startup focused on developing and commercializing new products utilizing the company’s proprietary synthetic cartilage technology – HYALEX. The material is unique in its ability to maintain low friction and low wear while supporting the high loads that human joints endure. The platform technology is initially being evaluated as part of a knee implant system to address unmet needs in the treatment of knee cartilage injuries.
https://ipd.health/ Implant Preservation Devices (IPD)has developed a handheld device to tackle a common, but devastating problem after joint replacement and fracture related surgeries, prosthetic joint infections (PJI) and Fracture related Infections (FRI). This device applies heat to implants using induction, effectively targeting, and eliminating bacteria that cause these infections. By reducing the risk of recurrent infections, it offers a quick, sterile, and convenient treatment option during surgery, potentially benefiting patients beyond just those undergoing joint replacements or fracture treatment.
https://www.kneevoice.com/. Kneevoice has designed a platform technology to capture the noise generated by the knee to evaluate cartilage damage and diagnose osteoarthritis. The platform consists of wearable knee sensors that records the sounds generated by the knee. This data is collected an analyzed by a neural network algorithm and generates a score evaluating the status of the cartilage.
https://moximed.com/. Moximed has developed an implantable shock absorber for patients with medial knee osteoarthritis.The MISHA device reduces the overall loading on the knee and serves as an alternative to pain medication, knee braces and joint-altering knee surgery. Placed during an outpatient procedure, the device provides 13kg (30 lbs.) of weight unloading to the knee.
https://my01.io/MY01 has developed a device to continuously monitor and manage acute compartment syndrome in muscles. The MY01 device is a sterile, single-use device that quickly measures muscle pressure following orthopedic surgery for trauma.
https://www.nanochon.com/Nanochon’s flagship product, Chondrograft™, is an off the shelf implant composed of 3D-printed nanomaterial polymer, designed to replace damaged cartilage while promoting natural tissue regeneration. This innovative solution offers a minimally invasive treatment for joint injuries, aiming to improve patient outcomes and reduce the need for total joint replacements long term.
https://novapproachspine.com/NovApproach Spine develops solutions for anterior lumbar spine surgery. The company’s OneLIF™ interbody cage is designed to enhance surgical versatility, enabling safer approaches for complex anatomical cases. By reducing the need for multiple backup implant systems, OneLIF™ aims to streamline procedures, lower costs, and improve efficiency. NovApproach Spine’s team includes experienced industry leaders and surgeons focused on advancing spinal surgery techniques.
https://www.orthopreserve.com/OrthoPreserve is developing an artificial meniscus implant aimed at addressing chronic knee pain and mobility issues resulting from meniscus injuries. Our proprietary technology is designed to closely replicate the structure and properties of the natural meniscus, with the goal of restoring knee function and preserving joint health. This minimally invasive device has the potential to become a new standard of care and displace more invasive procedures.
https://ossiform.com/Ossiform is the developer of fully resorbable patient-matched implants, tailored to improve bone healing outcomes in orthopedics and spine. According to Ossiform: We Print Bone™.
https://thinkpolarisar.com/ POLARISAR is pioneering a new era in surgery using mixed reality technology. The company is delivering what total joint robotic systems do in a mixed reality format. The company recently received FDA clearance for its first product, Stellar Knee, to measure, plan and guide a total knee arthroplasty procedure dynamically in real time.
https://www.reachortho.ca/. Reach Orthopaedics is developing a durable shoulder implant to treat middle-aged patients suffering from massive irreparable rotator cuff tears (MIRCT). Almost ten percent of the over-50 population has a MIRCT, but the middle-aged population is underserved by current treatment options. Designed by a team of orthopaedic surgeons and engineers with over 100-years of combined experience, Reach Orthopaedics’ novel implant restores shoulder alignment – increasing mobility and function, while reducing chronic pain.
https://revbio.com/RevBio, Inc., is a regenerative medicine company engaged in the development and commercialization of TETRANITE®, a synthetic, injectable, self-setting, and osteoconductive bone adhesive. The company is initially developing its adhesive biomaterial platform as a therapeutic device for a range of clinical applications in the dental, cranial, spinal, orthopaedic and animal health markets. The TETRANITE technology is novel and patented, with seven FDA approved pre-clinical and clinical trials currently underway. There are no such materials on the market today as surgeons currently rely on metallic fixation devices and often adjunctive bone stimulation materials to treat devasting injuries.
https://www.spartabiomedical.com/The first osseointegrative biomimetic knee cartilage implant.
https://spinepointusa.com/SpinePoint is developing next generation spine surgery implants. Differentiated ideas today for better outcomes tomorrow. Made by surgeons for surgeons.
https://www.traceorthopedi. Trace Orthopedics has developed a novel suture device to perform percutaneous soft tissue-to-bone fixation. The Trace tendon fastener system includes an implantable suture anchor encased inside a small delivery needle to be guided by ultrasound imaging in real time. Needle-based fixation will enable tendon repairs as outpatient procedures, filling a need across multiple patient groups with partial avulsion tears or total joint replacements needing extra stability.
https://visievision.com/VISIE is a 3D computer vision and spatial computing company researching, developing, and commercializing revolutionary optical scanners for robotic and navigated orthopedic, neuro, and spine surgery. VISIE’s proprietary imaging hardware and software combines the power of optical physics and deep tech to make the unseen seen in surgery.
https://www.zkrorthopedics.com/Millions of people in the U.S. suffer from degenerative arthritis of their knees. At least 20% of these patients have arthritis localized to their patellofemoral joint ( knee cap) with an addressable market of $2 Billion. Until now the only available options have been highly invasive surgeries, including knee replacement. The ZKR Patella LIFT implant offers patients a minimally invasive alternative to knee replacement at a significantly lower cost and a much faster recovery.