The donut hole in knee OA treatment: Why middle-aged knee patients are suffering.

I have been working on and thinking about knee OA for decades. FACT: There is a gaping hole in treatment options for many middle-aged patients with knee OA. Case in point: a 48-year-old weekend warrior, knees aching after a pickup soccer game, X-rays showing early cartilage wear, and a nagging limp that's stealing their prime years. They walk into an ortho clinic expecting options, only to hear, "You're too old for the fancy biologics, but way too young for a total knee replacement." Sound familiar? It's not just anecdotal—it's a systemic treatment gap that's leaving millions sidelined. ...


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