Mergers and Acquisitions in Orthopedics (by date)

Below is my list of key acquisitions in Orthopedics by announcement date.

Startups ⓢ dominate the list of acquired companies.

Read articles about ⓢ startups here

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Apr2020

• Apifix with Non-Fusion Scoliosis Technology is acquired by OrthoPediatrics for $37M up front.

Feb2020

• EOS Imaging is acquired by Alphatec Spine for $122M cash, stock and debt
• Fitbone Limb Lengthening System (Wittenstein SE) is acquired by Orthofix for $18M cash

Jan2020

• RTI Surgical OEM business is acquired by Montagu for $490M
• Arthrocare is acquired by Anika Therapeutics for $100M
• Parcus Medical is acquired by Anika Therapeutics for $95M

Dec2019

• ⓢ Verb Surgical is acquired by J&J for undisclosed 
• ⓢ IntraFuse is acquired by Conventus Orthopaedics for undisclosed

Nov2019

• Wright Medical is acquired by Stryker for $5.4B (6 X sales)
• Foot & Ankle products from Surgical Frontiers are acquired by CrossRoads Extremity Systems for undisclosed 

Sep2019

• ⓢ JointPoint is acquired by DePuy Synthes for undisclosed
• ⓢ Mobium Imaging is acquired by Stryker for $500M

Aug2019

• Stelkast in acquired by Globus Medical for $28M

Jul2019

• ⓢ Link Spine is acquired by Ceiling Spine for undisclosed
• ⓢ Atracsys Sarl (optical system for robotics) is acquired by Smith and Nephew for undisclosed

Jun2019

• ⓢ Vilex is acquired by OrthoPediatrics for $60M (5 X sales)

May2019

• ⓢ Titan Spine is acquired by Medtronic for undisclosed
• ⓢ Vertiflex is acquired by Boston Scientific for $465M

Mar2019

• ⓢ OMNI is acquired by Corin for undisclosed
• ⓢ OrthoSpace is acquired by Stryker for $220M
• ⓢ Osiris Therapeutics is acquired by Smith and Nephew for $660M

Feb2019

• ⓢ SEGWAY Orthopaedics is acquired by Trice Medical for undisclosed

Jan2019

• ⓢ Renovis Surgical Technologies is acquired by Kyocera for undisclosed

Dec2018

• ⓢ Centerix Orthopaedics acquired by Smith and Nephew for $105M

Nov 2018

• ⓢ Response Ortho acquired by WishBone Medical for undisclosed
• DJO Global acquired by Colfax, a non-medical company for $3.15B (2.6 X sales)
• ⓢ Paradigm Spine is acquired by RTI Surgical for $300M (7.5 X sales)

Sep 2018

• ⓢ Mazor Robotics is acquired by Medtronic for $1.6B (13.5 X sales last year)
• ⓢ Invuity is acquired by Stryker for $190M (4.9 X sales)

Aug 2018

• K2M is acquired by Stryker for $1.6B in a stock purchase at (5.2 X sales)

• ⓢ Cartiva acquired by Wright Medical for $435M cash (12.4 X sales)

• ⓢ EIT is acquired by DePuy Synthes for undisclosed in Germany

• Amedica’s spine business is acquired by CTL Medical for less than $10M

• ⓢ Surgimap is acquired by Globus Medical for undisclosed

• ⓢ Maxim Surgical is acquired by Fuse Medical for $3M in a stock transaction

May 2018

• ⓢ Expanding Orthopedics is acquired by CoreLink for undisclosed
• Corin Orthopaedics is acquired by Permira, an EU private equity group for undisclosed
• ⓢ Medical Enterprises is acquired by DePuy Synthes for its battery powered impactor for hip broaching for undisclosed
• Bradshaw Medical is acquired by In’Tech Medical for undisclosed

Apr 2018

• Paragon Medical is acquired by NN for $375M cash
• JRI Orthopaedics (UK) is acquired by AK Medical (China) for $24M

Mar 2018

• Skeletal Kinetics is acquired by Orthofic for $105M (7 X sales) 
• ⓢ SafeOp is acquired by AlphaTec Spine for $27M cash plus stock

Feb 2018

• ⓢ Orthotaxy, a French software-enabled surgery startup, is acquired by J&J DePuy for undisclosed

Jan 2018

• ⓢ Zyga Technologies is acquired by RTI Surgical for $35M (8.8 X sales)

Dec 2017

• ⓢ IMASCAP, a company with shoulder replacement pre-op planning software, is acquired by Wright Medical for $89M

Oct 2017

• ⓢ VEXIM is acquired by Stryker for $218M (~7 X sales)
• ⓢ Rotation Medical is acquired by Smith & Nephew for $210M
• Exactech is acquired by TPG Capital for $625M 

Sept 2017

• ⓢ Vertera Spine acquired by NuVasive for undisclosed

July 2017

• • ⓢ Sonoma Orthopedic Products acquired by Arthrex for undisclosed (no public announcements)
  • ⓢ Medshape’s ExoShape ACL portfolio is acquired by ConMed for undisclosed

• Thortex and Millennium Surgical acquired by Avalign Technologies for undisclosed

June 2017

• ⓢ Sentio nerve location technology for spine acquired by J&J DePuy Synthes for undisclosed.

Apr 2017

• ⓢ Spinal Elements acquired by Amendia for undisclosed
• ⓢ Technology from Tissue Regeneration Systems (3D printing tissue) is acquired by Depuy Synthes for undisclosed

Feb 2017

• OsteoMed’s spine assets are acquired by Wenzel Spine for undisclosed
• Exactech’s spine assets are acquired by ChoiceSpine for undisclosed

Jan 2017

• ⓢ Interventional Spine’s assets are acquired by J&J DePuy Synthes for undisclosed

Sept 2016

• ⓢ Ivy Sports Medicine is acquired by Stryker for undisclosed
• ⓢ Clinical Graphics, an imaging company to diagnose hip impingement, is acquired by Zimmer Biomet for undisclosed
• ⓢ Instratek’s portfolio of staple and hammertoe implants and MIS soft tissue recession instrumentation is acquired by Stryker for undisclosed

Aug 2016

• ⓢ NLT Spine acquired by SeaSpine for $53M

July 2016

• ⓢ French robotics company, Medtech with technology for MIS spine procedures, Medtech, is acquired by Zimmer Biomet for $77M
• ⓢ DFine is acquired by Merit Medical for $98M
• Wright Medical’s Tornier line of hips/knees is acquired by Corin for $38M

June 2016

• LDR Spine is acquired by Zimmer Biomet for $1B
• ⓢ Responsive Orthopedics acquired by Medtronic for undisclosed
• ⓢ ISTO Technologies is acquired by a private equity firm for undisclosed

May 2016

• ⓢ BME is acquired by DePuy Synthes for undisclosed 
• Symmetry Surgical is acquired by RoundTable Health Partners for $129M (1.5 X sales) 

Apr 2016

• Stanmore Implants acquired by Stryker for $52M cash
• ⓢ Cayenne Medical acquired by Zimmer-Biomet for $150M (7.5 X sales)
• ⓢ SafeWire acquired by Stryker for undisclosed

Jan 2016

• ⓢ Ellipse Technologies acquired by NuVasive for $410M cash (~10 X sales)   Read – An inside look at a successful startup – Ellipse Technologies
• ⓢ BST-CarGel acquired by Smith and Nephew for undisclosed

Dec 2015

• Lima Corporate is acquired by Private Equity firm EQT Partners for undisclosed
• ⓢ BioStructures is acquired by Bioventus for undisclosed

Nov 2015

• ⓢ Blue Belt Technologies with its Navio robotics system is acquired by Smith and Nephew for $275M

Sept 2015

• ⓢ Tornier’s Salto Total Ankle Replacement portfolio acquired by Integra LifeSciences for undisclosed

July 2015

• • ⓢ Custom Spine is acquired by Amendia for undisclosed

• • ⓢ X-Spine acquired by Bacterin for $107M and renames it Xtant Medical

• ⓢ Russian trauma and orthopaedics business acquired by Smith and Nephew for undisclosed
• ⓢ TEI Biosciences acquired by Integra LifeSciences for $312M (4X last years sales) 

June 2015

• ⓢ SpineSelect assets are acquired by Amendia for undisclosed

April 2015

• ⓢ Spinal Modulation acquired by St Jude for $215M total including original investment

February 2015

• ⓢ Baxano Surgical’s VEO Lateral Access & Interbody System is acquired by ChoiceSpine after the Baxano declared bankruptcy for an undisclosed sum.
• ⓢ Branch Medical Group, a Penn manufacturer, is acquired by Globus Medical for $53M
• ⓢ German Orthopedic Manufacturer acquired by Paragon Medical for an undisclosed sum

January 2015

• ⓢ BlueOrtho, a French joint navigation company, acquired by Exactech for $9.25M

November 2014

• ⓢ Optimized Ortho acquired by Corin for undisclosed

October 2014

• Wright Medical and Tornier merge in an all-stock trade deal
• ⓢ Allograft maker Transplant Technologies acquired by Globus for undisclosed
• ⓢ OrthoView acquired by Materialise for $12.3M
• ⓢ OsteoAMP produce line acquired by Bioventus for undisclosed 
• ⓢ ETEX acquired by Zimmer for undisclosed

August 2014

• Symmetry Surgical acquired by Tecomet for $450M

June 2014

• ⓢ Small Bone Innovations (SBI) acquired by Stryker for $375M in cash
• Covidien acquired by Medtronic for $42.9B

Apr 2014

• Biomet acquired by Zimmer for $13.35B

Feb 2014

• ArthroCare acquired by Smith and Nephew for $1.7B
• ⓢ Pivot Medical acquired by Stryker for undisclosed

Jan 2014

• ⓢ Solana Surgical, a foot & ankle startup, acquired by Wright Medical for $90M
• ⓢ OrthoPro, a foot & ankle startup, acquired by Wright Medical for $35M
• ⓢ Excelsius Surgical, robotics spine patient positioning startup, acquired by Globus Medical for undisclosed
• Covidien’s Duraseal product line a dural sealant is acquired by Integra LifeSciences for $235M

Oct 2013

• ⓢ Pipeline Orthopedics acquired by MAKO Surgical for $2.5M
• ⓢ Biotech Intl, French Foot & Ankle co, is acquired by Wright Medical for $80M
• Lanx is acquired by Biomet for undisclosed
• ⓢ Osiris’ culture expanded stem-cell business is acquired by Mesoblast for $100M

Sept 2013

• MAKO Surgical is acquired by Stryker for $1.65B (13 X sales)

June 2013

• Wright Medical’s Hip and Knee business is acquired by MicroPort for $290M
• ⓢ Pioneer Surgical Technology is acquired by RTI Biologics for $130M cash
• ⓢ NORMED Medizin-Technik, a German foot/ankle, hand and wrist company, acquired by Zimmer for undisclosed

May 2013

• ⓢ Knee Creations, a subchondralplasty startup, is acquired by Zimmer for an undisclosed amount.
• ⓢ Orthotic Holdings Inc, a Foot and Ankle plating company is acquired by Frazier Healthcare, a VC, for an undisclosed amount.

Mar 2013

• ⓢ Baxano is acquired by TranS1 for $26.3M

Jan 2013

• ⓢ Chinese Orthopedic company Trauson Holdings is acquired by Stryker for $764M
• ⓢ Exos Corporation is acquired by DJO Global for an undisclosed amount

Nov 2012

• ⓢ Biomimetic Therapeutics growth factor is acquired by Wright Medical for $190M cash and stock
• ⓢ Corin is acquired by Italian Orthopedic consortium 2IL Orthopaedics for $50M in cash

Oct 2012

• ⓢ Santa Clara Technology’s Titanium Expandable cage technology is acquired by Spine Wave for undisclosed

Sept 2012

• ⓢ China Kangui (joints, trauma, spine) is acquired by Medtronic for $816M cash
• ⓢ spine startup Phygen is acquired by Alphatec Spine for $15.2M stock and cash

Aug 2012

• ⓢ OrthoHelix’s Foot/Ankle trauma business is acquired by Tornier for $135M (4.6 X annual sales)

June 2012

• China’s Mindray Medical International, (MR) the world’s No. 3 maker of patient monitors, expanded into a new field last month by acquiring Wuhan Dragonbio Surgical Implant for $35.5M (4.6 X annual sales)
• ⓢ Spinal USA and Precision Medical of Mississippi acquired by Precision Spine for $72M

May 2012

• Kensey Nash acquired by DSM  for $360M

Apr 2012

• DePuy’s Trauma business is acquired by Biomet for $280M

Feb 2012

• Sandvic Medicial Solutions unit is acquired by Orchid Orthopedic Solutions for an undisclosed amount

Jan 2012

• ⓢ Synvasive Technologies acquired by Zimmer for an undisclosed amount
• ⓢ Cascade Medical Enterprises’ PRP & PRFM Technologies acquired by MTF for an undisclosed amount

Dec 2011

• Symmetry Medical acquired J&J’s Codman Surgical Instruments business for $165M
• ⓢ Synovis (soft tissue repair) acquired by Baxter for $325M

Nov 2011

• ⓢ ExtraOrtho acquired by Zimmer for an undisclosed amount

Sept 2011

• Impulse Monitoring acquired by NuVasive for $80M
• ⓢ Ascension Orthopedics acquired by Integra LifeSciences  for $65M
• ⓢ Suzhou Best acquired by Microport Orthopedics for $17M

July 2011

• ⓢ Salient Surgical acquired by Medtronic for $525M
• ⓢ PEAK Surgical acquired by  Medtronic for $120M
• KCI acquired by private equity firm Apax Partners for $6.3B
• Beijing Montagne Medical Device acquired by Zimmer for undisclosed
• Arthrocare’s Parallax and Contour spine lines acquired by NeuroTherm for undisclosed
• Robinson MedSurg acquired by Bacterin for $1M

June 2011

• ⓢ Memometal Technologies acquired by Stryker for $162M
• ⓢ Amplitude acquired by Apax France, a large joint manufacturer for $66M
• ⓢ Voyant Health acquired by  Brainlab for $10M
• TENET Medical Engineering acquired by Smith & Nephew for undisclosed
• Orchid Orthopedic Solutions acquired by Altor for undisclosed

May 2011

• ⓢ SeaSpine acquired by Integra Orthopaedics for $89M
• ⓢ Orthovita acquired by Stryker for $316M
• ⓢ Norian assets of Synthes acquired by Kensey Nash for $22M
• ⓢ Impliant was acquired by  Premia Spine for undisclosed
• ⓢ ProChon Biotech acquired by  Histogenics for stock

April 2011

• Synthes acquired by Johnson & Johnson for $21.3B
• Smith & Nephew Interventional Spine Pain Mgmt acquired by NeuroTherm for undisclosed

March 2011

• ⓢ Applied Spine Technologies was acquired by Rachiotek for undisclosed
• ⓢ NovaLign (certain IP) acquired by  FlexFix/VentureMD for undisclosed
• Beijing Wei Rui Li Medical (majority stake) was acquired by China Kanghui for undisclosed

Feb 2011

• Genzyme was acquired by Sanofi-aventis for $20.1B
• ⓢ NovaLign (certain intramedullary designs) acquired by Sonoma Orthopedic for undisclosed

Jan 2011

• Cardo Medical’s joint arthroplasty assets was acquired by Arthrex for undisclosed
• ⓢ Nerites acquired by Kensey Nash for $20M
• ⓢ Townsend Design acquired by Thuasne for undisclosed
• ⓢ Facet Solutions was acquired by Globus Medical for undisclosed

Dec 2010

• ⓢ Surgical Biologics acquired by MiMedx for undisclosed
• Stryker’s OP-1 bone growth factor acquired by Olympus for $60M
• Sodem Diffusion/SoPlus power tools acquired by Zimmer for undisclosed
• ⓢ Small Bone Innovations’s shoulder assets acquired by FX Solutions for undisclosed

Nov 2010

• Anspach was acquired by Synthes for undisclosed

Oct 2010

• ⓢ Porex Surgical acquired by Stryker for undisclosed
• ⓢ Acrobot was acquired by Stanmore Implants for undisclosed

Sep 2010

• ⓢ US Spine acquired by Amedica for undisclosed

Aug 2010

• Osteotech acquired by Medtronic for $123M
• ⓢ VertiFlex (certain spine assets) acquired by Exactech for undisclosed

July 2010

• Cytosol Labs was acquired by Biomet for undisclosed
• OrthoIT3 acquired by Global-Med Technologies for undisclosed

May 2010

• ⓢ Brighton Partners polyethylene technology was acquired by Exactech for $5.5M

April 2010

• ⓢ Eska Implants was acquired by Summit Medical for undisclosed
• ⓢ Synergetics’ Sonopet/Omni lines acquired by Stryker for $3M

March 2010

• ⓢ ApaTech was acquired by Baxter for $330M
• ⓢ Praxim Orthopaedic acquired by Synergy for undisclosed
• ⓢ iBalance was acquired by Arthrex for undisclosed
• ⓢ BoneGrafix (minority stake) was acquired by Global Biotech for undisclosed

Feb 2010

• ⓢ Advanced Bio-Surfaces’ OrthoGlide ankle was acquired by Memometal Technologies for undisclosed

Dec 2009

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