ISTO awarded a patent for Fusion Osteobiologic Bone Graft Extender and Substitute

ISTO’s Fusion Osteobiologic Granted Patent (Walter Eisner @ OTW) The U.S. Patent Office has issued a fundamental U.S. patent for the technology on which St. Louis-based ISTO Technologies, Inc.'s InQu Bone Graft Extender & Substitute is based. The product is a molecular entanglement of hyaluronic acid and a synthetic polymer to create a three-dimensional scaffold with a cell-friendly environment for bone growth. The U.S. patent (No. 8,192,759, "Matrix Made of Polyester Polymers Entangled with Hyaluronic Polymers Useful for Supporting Tissue Repair"), filed in July 2005 and granted on June 5, 2012, covers the unique biosynthetic structure of ISTO's product. The inventors are company President and CEO Mitchell Seyedin, Ph.D., and Robert Spiro. Patent Abstract The Abstract for the patent states: The present application discloses matrix compositions to support the repair of tissue defects such as an osteochondral injury. A matrix described herein comprises a polyester polymer entangled with a polysaccharide polymer. Also disclosed are methods of preparing a matrix, and methods of using a matrix in the repair of tissue. In certain configurations, a matrix can comprise polyester cross...


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