STUDY: ACI versus Microfracture – no difference

AUTOLOGOUS CHONDROCYTE IMPLANTATION AND MICROFRACTURE: NO DIFFERENCE (Orthopedics This Week) A randomized trial from several Norwegian facilities is indicating that the in vitro cultivation of autologous chondrocytes is not an improvement over microfracture. Researchers enrolled 80 patients with a single symptomatic chronic cartilage defect on the femoral condyle without general osteoarthritis (OA). Gunnar Knutsen, M.D., Ph.D., a co-author on the study, told OTW, “At 15 years follow-up, we found no significant clinical differences between the autologous chondrocyte implantation (ACI) and the m...


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